Six fire engines were called to the scene from the blaze near to Forest Hill station.
Fire teams brought a guy, a lady and 2 youngsters to safety after the roof of the house in Standstead Road, Lewisham, burst into flames soon after 10.30am today.
Firefighters saved four people, including two children, from the house fire in south-east London.
Dramatic images show fire teams inside a cherry picker trying to extinguish the blaze among plumes of thick, gray smoke.
The person was come to hospital by London Ambulance Service and also the lady and 2 children were assessed in this area by ambulance teams.
The street was cordoned off for around two hours while emergency services worked using the fire.